LigusActiv® Lovage rhizome Oil
 
Patent No.: CN200610034708.4
Botany:
This herb is the rhizomeof Ligusticum chuanxiong Hort.(family Umbelliferae) which is manly produced inSichuan Province.It is collected in summer, washed clean after getting rid ofthe hairy rootlets, baked dry, slice, and used unprepared or stir- baked withwine. Pungent inflavour, warm in property, acting on the liver, gallbladder andpericardium channels.
 Description:Ligusticum chuanxiong oil is extracted from the rhizome of Ligusticum chuanxiong Hort. (Umbelliferae) by CO2 extracted.
Latin Name: Ligusticumchuanxiong
Extract Method: By supercritical CO2 extraction.
Appearance: Clear,reddish brown liquid.
Specification: 45%（HPLC）
Active constituents:
Ligustilide(CAS#4431-01-0),
IUPAC:(3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one
MW: 190.24
Senkyunolide(CAS#:62006-39-7）
IUPAC:3-butyl-4,5-dihydro-3H-2-benzofuran-1-one
MW: 192.25
 
 
 MF: C12H14O2                  MF: C12H16O2

Traditional use
Rhizoma Chuanxiong(Ligusticum chuanxiong Hort. (Umbelliferae)), known as Chuanxiong in Chinese, acommonly used Traditional Chinese Medicinal (TCM) herb, has been used fortreating cardiovascular diseases in China for centuries (ChinaPharmacopoeia, 2005). In addition to raw herb preparations used in conventionalTCM practice, various Chuanxiong based proprietary products containingChuanxiong crude extract, especially Chuanxiong essentialoil extract, are alsoused clinically. For instance, Quick-acting Heart SavingPill (Chinese name:Suxiao Jiuxin Wan), a product manufactured for sublingual delivery, containsChuanxiong essential oil extract as the primary ingredient. In recent years,this product is one of the top five best-selling TCM-based cardiovascularproducts in China.Promote the circulation of blood and vital energy, expel wind and alleviatepain.
Pharmacological Actions:
1.Act on the centralnervous system: its aqueous solution in hibits mice’s autokineticmovement，prolongs the duration of pentobarbital’ hypnotic action，decreasing the excitement stimulating by Caffeine.
2. Act on cardiovascularsystem: relaxes the coronary arteries，provides increased blood supply to the heart muscle，decreases the cerebrovascular accidents; Lower blood pressure.
3. Act on the bloodsystem: inhibits the platelet aggregation, reduces the viscosity of the blood, andsuppresses the thrombosis.
4. Inhibits the growth ofintestinal gram-negative bacteria and skin fungi.
5. Inhibits orpreventsthe growth or development of malignant cells.
6. Clinical Application:It has a satisfactory effect on coronary heart disease, angina, ischemiccerebral vessel diseases, thrombus, headache, hepatitis disease, difficultmenstruation; improves visual acuity; prevents chronic mastitis etc